Neutrons Chart Atomic Map of COVID-19's Viral Replication Mechanism
Photo: Jill Hemman/ORNL, U.S. Dept. of Energy
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
Researchers at the Department of Energy's Oak Ridge National Laboratory used neutron scattering to identify key information to improve the effectiveness of drug inhibitors designed to block the virus's replication mechanism. The research is published in the Journal of Biological Chemistry.
The SARS-CoV-2 virus, which causes the COVID-19 disease, expresses long chains ...