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Oxygen Has Potential Benefits as a Therapy for Pulmonary Arterial Hypertension

AJMC | American Journal of Managed Care

Treatment guidelines only recommend oxygen (O2) therapy for patients with pulmonary arterial hypertension (PAH) if they develop hypoxemia, but a new review of evidence suggests the O2 has potential therapeutic benefit for all patients.

There are 4 classes of drugs used to treat PAH and they all target mechanisms involved with vasodilation of pulmonary arterial vessels, plus some patients are given calcium channel blockers. Trials of these therapies have limited information on functional improvements and 20% of patients still experience PAH worsening or related hospitalization, according to researchers.

Only a minority of patients with PAH who ...