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Using Genetics, Researchers Identify Potential Drugs for Early Treatment of COVID-19

Medical Xpress

Photo: Frank Curran

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

The findings appeared online in the journal Nature Medicine in March 2021.

Based on their analyses, the researchers are calling for prioritizing clinical trials of drugs targeting the proteins IFNAR2 and ACE2. The goal is to identify existing drugs, either FDA-approved or in clinical development for other conditions, that can be repurposed for the early management of COVID-19. Doing so, they say, will help keep people with the virus from ...