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A New Technique for Correcting Disease-Causing Mutations

Medical Xpress

Photo: Massachusetts Institute of Technology

medicalxpress.com

Gene editing, or purposefully changing a gene's DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual's DNA for therapeutic purposes. A novel method of gene editing that can be used for both purposes has now been developed by a team led by Guoping Feng, the James W. (1963) and Patricia T. Poitras Professor in Brain and Cognitive Sciences at MIT.

"This technical advance can accelerate the production of disease models in animals and, critically, opens up a brand-new methodology for correcting ...