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New Approach to Understanding Bone Strength Pays Dividends for Osteoporosis

Medical Xpress

Photo: Pixabay

medicalxpress.com

Researchers at the University of Virginia School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our risk of fracture.

The work offers important insights into osteoporosis, a condition that affects 10 million Americans, and it provides scientists potential new targets in their battle against the brittle-bone disease.

Importantly, the approach uses a newly created population of laboratory mice that allows researchers to identify relevant genes and overcome limitations of human studies ...