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Researchers Find Fat Burning Molecule in Mice

Phys.org

Photo: DOI: 10.1038/s41467-021-23595-x

Phys.org

Linked to serious health problems including cancer, diabetes, and cardiovascular disease, obesity affects more than a third of adults in the United States. Presently, there are few safe and effective nonsurgical therapeutic interventions available to patients with obesity.

Now, a multi-disciplinary team of researchers has demonstrated that a metabolic regulatory molecule called Them1 prevents fat-burning in cells by blocking access to their fuel source. Led by microscopy experts at Beth Israel Deaconess Medical Center (BIDMC) and metabolism experts at Weill Cornell Medicine and New York-Presbyterian, the study may contribute to the development of ...