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'Supermeres' May Carry Clues to Cancer, Alzheimer's Disease and COVID-19

Medical Xpress

Photo: Pixabay

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Researchers at Vanderbilt University Medical Center have discovered a nanoparticle released from cells, called a "supermere," which contains enzymes, proteins, and RNA associated with multiple cancers, cardiovascular disease, Alzheimer's disease, and even COVID-19.

The discovery, reported in Nature Cell Biology, is a significant advance in understanding the role extracellular vesicles and nanoparticles play in shuttling important chemical "messages" between cells, both in health and disease.

"We've identified a number of biomarkers and therapeutic targets in cancer and potentially in a number of other disease states that are cargo in these supermeres," said the paper ...