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Two DNA Defense Systems Behind Resilience of 7th Cholera Pandemic

Phys.org

Photo: Ronald Taylor, Tom Kirn, Louisa Howard/Wikipedia

Phys.org

Cholera is caused by the bacterium Vibrio cholerae, a waterborne pathogen that infects the gut of humans through contaminated water and food. When ingested, V. cholerae colonizes the gut’s inner surface, causing a watery diarrhea, that if left untreated, can lead to severe dehydration and death.

Cholera is still a problem, especially in less-developed or crisis-hit regions. The WHO reports that the ongoing seventh cholera pandemic is still responsible for up to four million infections, and up to 143,000 deaths each year.

Horizontal Gene Transfer

Only a few ...