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Study Reveals How Novel COVID-19 Manipulates Cells to Replicate

Phys.org

Photo: Orlando B. Scudero/ICB-USP

Phys.org

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

In laboratory tests, the researchers inhibited interaction between the molecules using a drug and thereby reduced viral replication by 15–20%. They expect their findings to contribute to the development of treatments for COVID-19 ...