Glycoprotein GPNMB is a Possible Biomarker for Parkinson’s Disease Risk
Computational, cell biological, and human tissue-based studies establish GPNMB as a risk gene and potential therapeutic target for Parkinson’s Disease (PD), researchers report. PD is a debilitating progressive neurodegenerative brain disorder that affects millions of people worldwide.
Diagnosis of the disease often relies on the presence of motor control symptoms that generally begin to appear after decades of disease progression. Thus, there is an urgent need to not only better understand the pathology of PD but also develop a panel of biomarkers that could identify individuals’ risk for developing PD before significant neurodegeneration occurs. Although ...