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Artificial Tissue Used to Research Uterine Contractions

Phys.org

Credit: David Elad

Phys.org

Advanced tissue engineering technologies allow scientists to mimic the structure of a uterus, enabling crucial research on fertility and disease.

In an APL Bioengineering article, researchers present two mechanobiology tools for experiments on synthetic or artificial uterine tissue. They wanted to study the negative effects of hyperperistalsis, contractions of the uterine wall that occur too frequently.

Throughout an individual's lifetime, the uterus undergoes spontaneous contractions of the uterine wall, which can induce uterine peristalsis, a specific wavelike contraction pattern. These contractions are important for many reproductive processes, such as the transportation of sperm prior ...