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Chronic Inflammation Alters the Evolution of Cells in the Colon, Study Finds

Medical Xpress

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In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level. Researchers from the Wellcome Sanger Institute and Cambridge University Hospitals found that the rate of DNA change within colon cells affected by IBD was more than double that in healthy colon, increasing the likelihood of these cells gaining DNA changes that could lead to cancer.

The study, published today (21 July) in Cell, also found that chronic inflammation associated with IBD ...