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Tracer Molecule May Improve Imaging Tests for Brain Injury

Medical Xpress

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medicalxpress.com

Researchers have validated a new radiolabeled molecule that can be used with imaging tests to accurately detect and characterize brain injury. The team, led by investigators at Massachusetts General Hospital (MGH), recently received clearance from the U.S. Food and Drug Administration (FDA) to initiate a first-in-human study with the strategy.

As described in the Journal of Cerebral Blood Flow & Metabolism, the novel tracer, called [18F]3F4AP, is designed to bind to potassium channels and is radiolabeled so it can be visualized through positron emission tomography (PET) imaging. Potassium channels in the ...