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Blood Clot-Busting Nanocapsules Could Reduce Existing Treatment's Side Effects

Phys.org

Photo: Pixabay/CC0 Public Domain

Phys.org

Tested on human blood in the lab, the selective nanocapsules could reduce the side effects of a major blood clot-dissolving drug, which include bleeding on the brain. If confirmed with animal tests, the nanocapsules could also make the drug more effective at lower doses.

Blood clots, also known as thrombi, are a key cause of strokes and heart attacks which are leading causes of death and ill-health worldwide. They can be treated with a clot-dissolving drug called tissue plasminogen activator (tPA) which disrupts clots to clear the blocked blood vessel and re-establish blood ...