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Evidence of Sleep-Dependent Brain Activity in Clearing Toxic Proteins & Preventing Alzheimer’s Disease

SciTechDaily

Photo: Feng Han and Xiao Liu @ The Pennsylvania State University

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Evidence of sleep-dependent low-frequency (<0.1 Hz) global brain activity in the clearance of Alzheimer’s disease-related toxin buildup is presented in research published today (June 1, 2021) in the open-access journal PLOS Biology by Xiao Liu and colleagues at The Pennsylvania State University. This neuronal activity was more strongly linked with cerebrospinal fluid flow in healthy controls than higher-risk groups and patients, and the findings could serve as a potential imaging marker for clinicians in evaluating patients.

The development of Alzheimer’s disease is believed to be ...